解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Heart failure is a complex syndrome that affects almost all organs and systems of the body. Signs and symptoms of organ dysfunction, in particular kidney dysfunction, may be accentuated or become evident for the first time during acute decompensation of heart failure. Cardiorenal syndrome has been defined as the simul...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/S0025-7753(14)70079-X
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Anal intraepithelial neoplasia is considered a precursor lesion of anal squamous carcinoma. The population with increased risk of this conditions are immunocompromised individuals, especially HIV-infected, with anal sex practices. The aim of this study was to describe the sexual habits of patients who were s...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2013.05.047
更新日期:2014-02-20 00:00:00
abstract::GLP-1 receptors agonists have been a substantial change in treatment of type 2 diabetes mellitus, and its weekly administration has broken pre-established schemes. Daily exenatide is administered every 12 hours (BID) subcutaneously, while weekly exenatide is administered once a week. Both molecules share a common mech...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/S0025-7753(14)70105-8
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Although elder abuse is not a new phenomenon, it remains hidden. There have been carried out various preliminary studies about the prevalence of elder abuse in different countries. The aim of this study is to estimate the prevalence of suspicion of elder abuse in old persons without cognitive i...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medcli.2012.09.048
更新日期:2013-12-21 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To analyze the effects of an aquatic biodance based therapy on sleep quality, anxiety, depression, pain and quality of life in fibromyalgia patients. PATIENTS AND METHOD:Randomized controlled trial with 2 groups. Fifty-nine patients were assigned to 2 groups: experimental group (aquatic biodan...
journal_title:Medicina clinica
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.medcli.2012.09.036
更新日期:2013-12-07 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Pertussis remains an important cause of morbimortality despite current vaccination strategies. This study was designed to describe the results and characteristics of close contacts of pertussis cases diagnosed in children less than 16 years in a tertiary hospital in Barcelona. PATIENTS AND ME...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.09.017
更新日期:2013-11-02 00:00:00
abstract::Bipolar disorder is a chronic and recurrent mood disorder, which may severely impact on the patient's global functioning. It has been estimated that approximately 1.6% of the population is affected. A long delay in diagnosis and an excessive disparity in the treatment of these patients have been detected. Within the Q...
journal_title:Medicina clinica
pub_type: 杂志文章,实务指引
doi:10.1016/j.medcli.2013.05.023
更新日期:2013-10-05 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The aim of this cross-sectional study was to compare the prevalence of target organ damage (TOD) and established cardiovascular disease (CVD) in a cohort of nondiabetic hypertensive patients with 3 or more cardiovascular risk factors (CVRF) against a group of hypertensives with type 2 diabetes....
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.05.032
更新日期:2013-10-05 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To establish the factors associated with the presence of non-alcoholic fatty liver disease (NAFLD) and evaluate the influence of each component constituting the metabolic syndrome (MS) and the risk of developing NAFLD. PATIENTS AND METHODS:We performed a multicenter, population-based, observa...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medcli.2012.11.034
更新日期:2013-09-21 00:00:00
abstract::Osteoarthritis and osteoporosis are both common conditions in the elderly but their association has long remained obscure. Recently published studies show that patients with osteoarthritis have higher bone mass but no corresponding decrease in fracture risk. This has been proposed to be due to an increased rate of fal...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2013.01.036
更新日期:2013-09-07 00:00:00
abstract::In this study, we review the efficacy and safety limitations of insulin-dependent oral antidiabetic agents. In terms of efficiency, the main drawback of metformin, sulfonylureas, gliptins and -to a lesser extent-glitazones is durability. No drug per se is able to maintain stable blood glucose control for years. Metfor...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/S0025-7753(13)70059-9
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The pprevalence of extended-spectrum beta-lactamase (ESBL) producing gram-negative bacilli has increased in recent years. The aim of this study is to estimate the prevalence of infection/colonization due to theses microorganisms per 100 admissions and its trend during the period 2007-2010. PAT...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.03.034
更新日期:2013-07-07 00:00:00
abstract::Uterine fibroids are the most common benign tumours that affect women of reproductive age and they represent the main indication for surgery for benign uterine pathology. In 25% of cases, they become clinically apparent, causing heavy menstrual bleeding, pelvic pain and/or infertility. Therefore, fibroids have a notab...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/S0025-7753(13)70045-9
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Urban air pollutants are composed of a heterogeneous mixture of substances in gas and aerosol states. The aim of this study was to compare the effects caused by exposure to contaminants in the gas phase and atmospheric particles in ambient air in patients hospitalized for acute coronary syndro...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.05.040
更新日期:2013-06-18 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Hypertension is the most prevalent risk factor in the community. The aim of this study was to describe the risk factors for the progression of blood pressure (BP) from correct values. SUBJECTS AND METHODS:Prospective and observational study with 7 years follow-up. BP>140/90 mmHg was considered...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.09.026
更新日期:2013-06-04 00:00:00
abstract:BACKGROUND AND OBJECTIVE:An important input to decision-making and health planning is a consistent and comparative description of the population health status. The purpose of this study was to describe the burden of disease in the Region of Valencia (Spain). MATERIAL AND METHODS:Disability-adjusted life years (DALYs) ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.01.028
更新日期:2013-04-20 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Around 75% of the population in our country will die as a consequence of chronic advanced diseases. Advanced chronic care is one of the major challenges for public health systems. This study describes the development of a tool to identify patients with advanced chronic diseases and life limited...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.06.027
更新日期:2013-03-16 00:00:00
abstract::Community-acquired pneumonia (CAP) is an infectious respiratory disease with an incidence that ranges from 3 to 8 cases per 1,000 inhabitants per year. This incidence increases with age and comorbidities. Forty per cent of CAP patients require hospitalization and around 10% of these patients are admitted in an Intensi...
journal_title:Medicina clinica
pub_type: 共识发展会议,杂志文章,实务指引
doi:10.1016/j.medcli.2012.09.034
更新日期:2013-03-02 00:00:00
abstract::Osteoporosis is a major cause of fractures in elderly women. Bone densitometry is used in order to detect osteoporosis. It has been observed can also be analyzed in the jawbone. The osteoporosis may be associated with resorption of the residual ridge, periodontitis and tooth loss; also the same treatments can affect t...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2012.05.029
更新日期:2013-02-16 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In the last years, a study is being conducted about exposure to asbestos among shipyards workers in order to know the diagnosis of the diseases associated with the exposure. Our goal was to know the asbestos pulmonary contents in this population. MATERIAL AND METHODS:We obtained autopsy pulmon...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.01.023
更新日期:2013-02-16 00:00:00
abstract::Neutrophils play a key role in the innate immune system, providing the first line of host defense. In addition to their ability to eliminate pathogens by phagocytosis and antimicrobial secretions, it has recently been shown that neutrophils can trap and kill microorganisms by the release of extracellular structures co...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2012.04.022
更新日期:2013-01-19 00:00:00
abstract:BACKGROUND AND OBJECTIVE:White coat effect (WCE) (i.e., the difference between office blood pressure [OBP] and awake ambulatory blood pressure monitoring [ABPM]) may be present in hypertensive individuals. The relationship between occurrence of WCE and target organ damage (TOD) has not yet been assessed in true resista...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.04.031
更新日期:2013-01-05 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The early detection of inborn errors of metabolism by mass spectrometry allows expanding the traditional neonatal screening of phenylketonuria and congenital hypothyroidism to test for aminoacidopathies, fatty acid oxidation disorders and organic acid metabolic disorders. Cystic fibrosis and bi...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2011.10.007
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The objective is to identify the features associated with next year hospital admissions among elderly dependent patients living at home (EDLH) and visited by primary care teams at their home setting. PATIENTS AND METHOD:Longitudinal cohort study of a sample of EDLH patients admitted to a home ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.01.030
更新日期:2012-11-03 00:00:00
abstract::Venous thromboembolism is a frequent complication in cancer patients and affects their morbidity and mortality. The risk of this event differs according to the characteristics of the tumor, the patient's circumstances, and the treatments provided. Although the benefits of thromboprophylaxis in certain subgroups of pat...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/S0025-7753(12)70039-8
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The vanilloid receptor TRPV1 is a molecular integrator of painful stimuli. Several recent studies suggest that TRPV1 may play a role in development and maintenance of chronic pain. In an attempt to determine if genotypic variations in TRPV1 gene could be involved in the susceptibility to suffer...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2011.10.028
更新日期:2012-06-02 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Information about the prevalence of chronic kidney disease (CKD) in the population treated in primary care is scarce. The aim of this study was to assess the prevalence of CKD in Spanish hypertensive women aged 64 years or older, and to determine possible associated factors. PATIENTS AND METH...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medcli.2011.03.038
更新日期:2012-05-05 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The aim of our study was to identify the rate of diabetic patients treated for hypothyroidism and compare them with a group without type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS:We reviewed the computerized clinical records of 5161 patients. We identified diabetic patients treated with...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2011.08.009
更新日期:2012-04-28 00:00:00
abstract::Weight loss can improve metabolic control in patients with type 2 diabetes mellitus but the results of conventional therapy in this respect have been discouraging. Besides achieving significant and sustained weight loss, bariatric surgery can improve or resolve type 2 diabetes mellitus in the majority of patients. Ana...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2011.04.009
更新日期:2012-04-14 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to validate the ability of the Finnish Diabetes Risk Score (FINDRISC) to predict the risk of DM2 in a population of south-eastern Spain (Pizarra Study). SUBJECTS AND METHODS:The Pizarra Study is a population-based prospective study developed in the town of Pizarra (Má...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2011.05.025
更新日期:2012-04-14 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To evaluate the management of phenylketonuria (PKU) in Spanish metabolic units and to develop a patients registry. PATIENTS AND METHODS:PKU patients diagnosed and/or followed up in Spain, with phenylalanine values before treatment > 360 μmol/L. Registered anonymous data are those yielded by th...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medcli.2011.03.037
更新日期:2012-03-03 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To include a specific antibiotic in the empiric therapy, it is necessary to predict when a nosocomial pneumonia (NP) is caused by methicillin-resistant Staphylococcus aureus (MRSA). We have developed a model for the prediction of the probability of a NP being caused by MRSA, when the carrier st...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2011.05.028
更新日期:2012-02-18 00:00:00
abstract::We discuss different interpretations of the term poison as well as the need of bringing up to date the changes in this matter according to the science progress. A clear and exact definition is proposed after analysing the factors that affect the relativity of the concept and its boundaries. The proposal for a definiti...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2011.02.002
更新日期:2012-02-18 00:00:00
abstract::The hepatitis E virus is an RNA virus with 4 genotypes. Genotypes 1 and 2 only affect humans and produce epidemic acute hepatitis in endemic regions (Asia and Africa). Genotypes 3 and 4 are considered a zoonosis and produce episodic acute hepatitis in non-endemic areas (America and Europe). However, in the last 3 year...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2011.02.003
更新日期:2012-02-04 00:00:00
abstract::Noninvasive ventilation (NIV) utilization has experienced an exponential growth in the last 25 years immediately after the introduction of the positive pressure and the nasal mask. Patients with acute, chronic and acute on chronic respiratory failure are candidates to be treated by this therapeutic modality. Its utili...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2011.10.003
更新日期:2011-12-10 00:00:00
abstract::The aim of this work is to show the changes observed in the health profile according to gender in 2006 with respect to 1994 of the population of Catalonia, through the comparison of data obtained in 1994 and 2006 from the Encuesta de Salud de Cataluña. The increase of the level of studies of the population has tended ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/S0025-7753(11)70025-2
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To assess the safety and efficacy of insulin analogues versus human insulin in pregnant women with pregestational diabetes. PATIENTS AND METHODS:We collected data on pregnant women with type 1 or type 2 diabetes who were attended at the Diabetes and Pregnancy Unit between January 1998 and Apri...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2010.11.021
更新日期:2011-11-19 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Cardiomyopathy in childhood is a rare entity. Inborn errors of metabolism can cause myocardial involvement by several mechanisms. PATIENTS AND METHODS:Patients under 16 years diagnosed with cardiomyopathy and EIM in a period of 11 years (1998-2009) were included. RESULTS:A total of 12 patient...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2011.06.019
更新日期:2011-11-19 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To validate four instruments to detect domestic violence in health-care settings against external criteria -Index of Spouse Abuse (ISA), Psychological Maltreatment of Women Inventory short form (PMWI-SF), Woman Abuse Screening Tool (WAST), Partner Violence Screen (PVS)- and to assess the conco...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2010.11.038
更新日期:2011-10-08 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Fibromyalgia is considered as a combination of physical, psychological and social disabilities. The purpose of the present study was to determine the benefits of aerobic exercise program and progressive relaxation techniques on anxiety, quality of sleep, depression and quality of life in patien...
journal_title:Medicina clinica
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.medcli.2010.09.045
更新日期:2011-10-08 00:00:00